Human health is facing a severe threat from pathogenic infections, particularly the emergence of antibiotic-resistant microorganisms has deepened the public's fear. The series of clinical diseases caused by microbial infections is constantly increasing. Therefore, they have become one of the hot topics of public health. Polymer materials display unprecedented advantages as effective antimicrobial materials due to their good biocompatibility, easy structure modification, and little proneness to developing drug resistance of pathogens. Herein, we put forward a summarization of research focused on conjugated and non-conjugated polymer materials in the field of killing pathogens in recent years with various therapeutic modes including non-photo inductive therapy, photothermal therapy (PTT) and photodynamic therapy (PDT). The current status, challenges, and future prospects of antimicrobial nanostructured materials (aNSMs) are addressed at the same time, devoted to the design and synthesis of aNSMs for ever-increasing demand of killing pathogens.

中文翻译：

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用于抗菌治疗和抗药性的功能高分子纳米材料的设计

人体健康正面临着由病原体感染引起的严重威胁，特别是对抗生素具有抗药性的微生物的出现加深了公众的恐惧。由微生物感染引起的一系列临床疾病在不断增加。因此，它们已成为公共卫生的热门话题之一。聚合物材料具有良好的生物相容性，易于结构修饰，几乎不易发展病原体的耐药性，因此作为有效的抗菌材料显示出前所未有的优势。本文中，我们提出了近年来在共轭和非共轭高分子材料杀灭病原体领域的研究综述，包括非光诱导疗法，光热疗法（PTT）和光动力疗法（PDT）等多种治疗方式。当前状态，