Neuronal circuits internally regulate electrical signaling via a host of homeostatic mechanisms. Two prominent mechanisms, synaptic scaling and structural plasticity, are believed to maintain average activity within an operating range by modifying the strength and spatial extent of network connectivity using negative feedback. However, both mechanisms operate on relatively slow timescales and thus face fundamental limits due to delays. We show that these mechanisms fulfill complementary roles in maintaining stability in a large network. In particular, even relatively, slow growth dynamics improves performance significantly beyond synaptic scaling alone.

中文翻译：

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树突状运输：突触缩放和结构可塑性

神经元电路通过多种稳态机制在内部调节电信号传导。据信，两个重要的机制，即突触缩放和结构可塑性，可以通过使用负反馈修改网络连接的强度和空间范围，将平均活动维持在一个操作范围内。但是，这两种机制都在相对较慢的时间尺度上运行，因此由于延迟而面临基本限制。我们表明，这些机制在维持大型网络的稳定性中起着互补的作用。尤其是，即使相对而言，缓慢的生长动力也可以显着改善性能，而不仅仅是单独的突触缩放。