Herein, we describe the selective positioning of metal–organic framework (MOF) nanoparticles UiO-66 (Universitet i Oslo; Zr₆O₄(OH)₄(bdc)₆; bdc^2– = benzene-1,4-dicarboxylate) and MIL-101 (Matérial Institut Lavoisier, Cr₃O(OH) (H₂O)₂(bdc)₃) at defined positions on a patterned substrate. For this purpose, patterned alkyne- and carboxylic acid-terminated self-assembled organic monolayer (SAM)-modified silicon surfaces were prepared by liquid immersion and microcontact printing (μCP). Preformed UiO-66 and MIL-101 nanometer-sized MOFs (NMOFs) were synthesized by solvothermal synthesis, and the nanocrystallite particles’ exterior surface was functionalized in order to generate reactive sites (such as azides and amines) at the NMOFs. Copper-catalyzed alkyne azide cycloaddition and N-hydroxysuccinimide-mediated amide formation were used to selectively position the NMOFs at the surface of pre-patterned substrates. The resulting surfaces were thoroughly investigated by scanning electron microscopy, infrared spectroscopy, and X-ray photoelectron spectroscopy, confirming the validity of the presented approach. We hope that our research paves the way for microsystem integration of NMOFs, for example, in microfluidic devices/reactors, and further investigation of their enhanced catalytic activity.

中文翻译：

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纳米尺寸的金属-有机骨架颗粒在图案化基材表面的选择性定位

在这里，我们描述金属-有机骨架（MOF）纳米粒子UiO-66的选择性定位（奥斯陆大学； Zr ₆ O ₄（OH）₄（bdc）₆； bdc ^2– =苯-1,4-二羧酸酯）和MIL-101（材料研究所Lavoisier，Cr ₃ O（OH）（H ₂ O）₂（bdc）₃）在图案化基材上的指定位置。为此，通过浸液和微接触印刷（μCP）制备了图案化的以炔烃和羧酸为末端的自组装有机单层（SAM）改性的硅表面。通过溶剂热合成法合成了预先形成的UiO-66和MIL-101纳米级MOF，并对纳米微晶颗粒的外表面进行了功能化处理，以便在NMOFs上产生反应位点（例如叠氮化物和胺）。铜催化的叠氮炔环加成和氮-羟基琥珀酰亚胺介导的酰胺形成用于将NMOF选择性地定位在预图案化的基底的表面上。通过扫描电子显微镜，红外光谱和X射线光电子能谱对所得表面进行了彻底研究，证实了所提出方法的有效性。我们希望我们的研究为NMOF的微系统集成铺平道路，例如在微流体装置/反应器中，以及对其增强的催化活性的进一步研究。