A method for determination of related impurities in the new anxiolytic drug substance GML-3 was developed. HPLC and TLC techniques that could identify starting materials and synthetic intermediates and quantify them and unidentified impurities with contents of 0.05% and less in the drug substance were developed. The proposed techniques could be used further for quality control of GML-3 drug substance.

中文翻译：

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测定GML-3药物中相关杂质的方法的开发：一种具有抗焦虑特性的新化合物

建立了一种新的抗焦虑药物GML-3中相关杂质的测定方法。开发了可以鉴定原料和合成中间体并对其进行定量的HPLC和TLC技术，并开发了原料药中含量不超过0.05％的未鉴定杂质。所提出的技术可以进一步用于GML-3原料药的质量控制。