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A practical approach for extracting mechanical properties of microcapsules using a hybrid numerical model
Microfluidics and Nanofluidics ( IF 2.8 ) Pub Date : 2020-11-25 , DOI: 10.1007/s10404-020-02401-y
A. Rahmat , J. Meng , D. R. Emerson , Chuan-Yu Wu , M. Barigou , A. Alexiadis

In this paper, the deformation of compliant microcapsules is studied in narrow constrictions using a hybrid particle-based model. The model combines the Smoothed Particle Hydrodynamic (SPH) method for modelling fluid flow and the Mass Spring Model (MSM) for simulating deformable membranes. The model is initially validated for the dynamics of microcapsules in shear flow. Then, several quantitative parameters such as the deformation index, frontal tip and rear tail curvatures and the passage time are introduced and their variations are studied with respect to capillary number and constriction size. Subsequently, a dependency analysis is performed on these quantitative parameters and some recommendations are made on fabrication of microfluidic devices and analysis of microcapsules for extracting their mechanical properties. It is revealed that the deformation index and frontal tip and rear tail curvatures are the most suitable parameters for correlating the elastic properties to the dynamics of microcapsules.



中文翻译:

一种使用混合数值模型提取微胶囊力学性能的实用方法

在本文中,使用基于混合粒子的模型在狭窄的狭窄区域中研究了顺应性微胶囊的变形。该模型结合了用于对流体流动进行建模的平滑粒子流体动力学(SPH)方法和用于模拟可变形膜的质量弹簧模型(MSM)。该模型最初针对剪切流中微胶囊的动力学进行了验证。然后,介绍了几个定量参数,例如变形指数,前,后尾曲率和通过时间,并研究了它们在毛细管数和收缩尺寸方面的变化。随后,对这些定量参数进行依赖性分析,并对微流体装置的制造和微胶囊的分析提出一些建议,以提取其机械性能。

更新日期:2020-11-25
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