Abstract

The communication deals with the eco-friendly synthesis and X-ray crystal structure of an organic carbonitrile, namely 6-amino-3-phenyl-4-(pyridin-4-yl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile. The title compound was synthesized in 89% yield by following a simple, straightforward and highly efficient multicomponent one-pot protocol under the excellent catalytic influence of non-toxic trisodium citrate dihydrate under ambient conditions. X-ray diffraction studies reveal the packing of molecules in the crystal, which is strongly influenced by both intra and intermolecular hydrogen interactions. In addition, aromatic π–π interactions stabilize the molecular chains propagating along [001].

中文翻译：

---

新型6-氨基-3-苯基-4-（吡啶-4-基）-2,4-二氢吡喃并[2,3-c]吡唑-5-碳腈的X射线晶体结构分析

摘要

交流涉及有机腈的环保合成和X射线晶体结构，即6-氨基-3-苯基-4-（吡啶-4-基）-2,4-二氢吡喃[2,3- c ]吡唑-5-腈。通过在环境条件下无毒柠檬酸三钠二水合物的出色催化作用下，遵循简单，直接和高效的多组分一锅操作方案，以89％的产率合成标题化合物。X射线衍射研究揭示了晶体中分子的堆积，这受分子内和分子间氢相互作用的强烈影响。此外，芳族π-π相互作用可稳定沿[001]传播的分子链。