当前位置: X-MOL 学术Langmuir › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Self-Assembly Fabrication of Honeycomb-like Magnetic–Fluorescent Fe3O4–QDs Nanocomposites for Bimodal Imaging
Langmuir ( IF 3.9 ) Pub Date : 2020-11-24 , DOI: 10.1021/acs.langmuir.0c00077
Jincheng Li 1 , Jialei Zhang 1 , Zengchao Guo 1 , Hui Jiang 1 , Haijun Zhang 2 , Xuemei Wang 1
Affiliation  

Magnetic–fluorescent nanocomposites have a tremendous potential in biomedicine realms as a revolutionary dual-modality probe tool for more accurate medical detection. However, complicated and inefficient postprocesses pose obstacles to obtaining high-quality magnetic–fluorescent nanocomposites. Thus, the fabrication of magnetic–fluorescent functional nanocomposites via a simple, effective, and ideal method remains a challenge and is still waiting to be tapped. The new synthesis approaches are becoming impending demands and probably enable us to address these above-mentioned problems. In this contribution, we present a novel self-assembly synthesis route for the construction of magnetic–fluorescent bimodal imaging nanocomposites rather than adopting sophisticated postpreparative processes. The Fe3O4 and quatum dots (QDs) nanocomposites were cross-linked fleetly by cerium(III) ion driven coordination bonds in which the cerium(III) ions served as the cross-connecting node and the carboxylate groups acted as bridging ligands. The potential application for dual-modality imaging capability was validated on tumor-bearing mice. This ingenious strategy was extremely efficient and handy for the magnetic–fluorescent Fe3O4–QDs nanocomposite construction. Significantly, our cerium(III) ion driven self-assembly method probably has a wide applicability for nanoparticles and organic molecules containing carboxyl groups but extensive explorations are still necessary.

中文翻译:

蜂窝状磁性荧光Fe 3 O 4 -QDs纳米复合材料的自组装制备双峰成像。

磁性荧光纳米复合材料作为一种革命性的双模式探针工具,在生物医学领域具有巨大的潜力,可以实现更精确的医学检测。但是,复杂且效率低下的后处理过程阻碍了获得高质量的磁性荧光纳米复合材料。因此,通过简单,有效和理想的方法制备磁性-荧光功能纳米复合材料仍然是一个挑战,并且仍在等待开发。新的合成方法正成为迫在眉睫的需求,可能使我们能够解决上述问题。在这项贡献中,我们提出了一种新颖的自组装合成途径,用于构建磁性-荧光双峰成像纳米复合材料,而不是采用复杂的后制备方法。铁3 O4和量子点(QDs)纳米复合材料通过铈(III)离子驱动的配位键快速交联,其中铈(III)离子充当交叉连接节点,羧酸酯基团充当桥连配体。双模态成像功能的潜在应用已在荷瘤小鼠身上得到验证。这种巧妙的策略对于磁性-荧光Fe 3 O 4 -QDs纳米复合材料结构极为有效且方便。值得注意的是,我们的铈(III)离子驱动的自组装方法可能对具有羧基的纳米粒子和有机分子具有广泛的适用性,但仍需要进行广泛的探索。
更新日期:2020-12-08
down
wechat
bug