Phosphines have, in combination with transition metals, played a pivotal role in the rapid development of efficient catalytic processes. Caged phosphines constitute a class of three‐dimensional scaffolds providing unique control over steric and electronic properties. The versatility of the caged phosphine ligands has been demonstrated elegantly by the groups of Verkade, Gonzalvi as well as Stradiotto. Our research group has also been working extensively for the past several years in the development of 1,3,5‐triaza‐7‐phosphaadamantane‐based caged ligands and in this personal note we have summarized these applications pertaining to the modification of biologically useful nucleosides and heteroarenes.

中文翻译：

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1,3,5-三氮杂-7-磷杂金刚烷（PTA）衍生的笼形膦用于钯催化的核苷和杂芳烃的选择性功能化

磷与过渡金属的结合在高效催化过程的快速发展中起着举足轻重的作用。笼状膦构成一类三维支架，可对空间和电子特性进行独特控制。Verkade，Gonzalvi和Stradiotto小组已很好地证明了笼状膦配体的多功能性。在过去的几年中，我们的研究小组也一直在广泛研究基于1,3,5-三氮杂-7-磷金刚烷的笼型配体，在本篇个人笔记中，我们总结了这些与修饰生物学上有用的核苷有关的应用和杂芳烃。