Abstract

3-Phenyl-2-(prop-2-en-1-ylsulfanyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one reacted with 4-methoxyphenyltellurium trichloride in a regioselective manner to give angularly fused 1-{[dichloro(4-methoxyphenyl)-λ⁴-tellanyl]methyl}-4-oxo-5-phenyl-1,2,4,5,6,7,8,9-octahydrobenzo[4,5]thieno[3,2-e][1,3]thiazolo[3,2-a]pyrimidinium chloride. Electrophilic cyclization of 2-(prop-2-en-1-ylsulfanyl)- and 2-(2-methylprop-2-en-1-ylsulfanyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-ones with 4-methoxyphenyltellurium trichloride afforded linearly fused 3-{[dichloro(4-methoxyphenyl)-λ⁴-tellanyl]methyl}-2,3,6,7,8,9-hexahydro-5H-benzo[4,5]thieno[2,3-d][1,3]thiazolo[3,2-a]pyrimidin-5-one hydrochlorides. Regardless of the reactant ratio, the products were isolated as 1:1 complexes with 4-methoxyphenyltellurium trichloride.

中文翻译：

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对-甲氧基苯基碲三氯化物对2-（烯基硫烷基）噻吩并[2,3-d]嘧啶-4（3 H）-的分子内亲电环化的区域选择性

摘要

3-苯基-2-（丙-2-烯-1-基硫烷基）-5,6,7,8-四氢苯并[4,5]噻吩并[2,3 - d ]嘧啶-4（3 H）-反应了与三氯化以区域选择性的方式4 methoxyphenyltellurium，得到稠合的角度1 - {[二氯（4-甲氧基苯基）-λ ⁴ -tellanyl]甲基} -4-氧代-5-苯基- 1,2,4,5,6， 7,8,9-八氢苯并[4,5]噻吩并[3,2- e ] [1,3]噻唑并[3,2- a ]氯化嘧啶鎓。2-（prop-2-en-1-ylsulfanyl）-和2-（2-methylprop-2-en-1-ylsulfanyl）-5,6,7,8-tetrahydrobenzo [4,5] thieno [的亲电环化[ 2,3- d ]嘧啶-4（3 H ^） -酮与4- methoxyphenyltellurium三氯化，得到线性稠合3 - {[二氯（4-甲氧基苯基）-λ ⁴-tellanyl] methyl} -2,3,6,7,8,9-六氢-5 H-苯并[4,5]噻吩并[2,3- d ] [1,3]噻唑并[3,2- a ]嘧啶5一盐酸盐。不管反应物的比例如何，都将产物与4-甲氧基苯基三氯化碲按1：1的配合物分离。