There has been a developing interest in the green-mediated synthesis of metal nanorods (NRs), especially from plants. However, there is no published report on the synthesis of ZnO NRs prepared via Cyrtrandroemia nicobarica leaf extract. The formation of ZnO NRs was confirmed by using x-ray diffraction, a Fourier transform infrared spectrometer, Brunauer–Emmett–Teller analysis, scanning electron microscope-energy-dispersive x-ray spectroscopy, and transmission electron microscopy analyses. The result revealed that the acquired ZnO NRs contain a unique surface area and excellent particle size. The photocatalytic and antioxidant activities of ZnO NRs were also evaluated in this study. The toxic nature of the obtained ZnO NRs was analyzed using the Daniorerio model, and the results showed that it was nontoxic. The anticancer activity of ZnO NRs was also analyzed using a human lung cancer cell line (A549), and excellent results were observed about the cancer cell death pathway. Hence, it was confirmed that the acquired ZnO NRs were nontoxic and had magnificent antibacterial and antioxidant activities. They can be used as an anticancer drug for health-care implementations.

中文翻译：

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Cyrtrandroemia nicobarica 合成的 ZnO NRs：癌症治疗的新工具

人们对绿色介导的金属纳米棒 (NRs) 合成越来越感兴趣，尤其是从植物中合成。然而，目前还没有关于通过 Cyrtrandroemia nicobarica 叶提取物制备 ZnO NRs 的合成报道。通过使用 X 射线衍射、傅里叶变换红外光谱仪、Brunauer-Emmett-Teller 分析、扫描电子显微镜-能量色散 X 射线光谱和透射电子显微镜分析证实了 ZnO NRs 的形成。结果表明，获得的 ZnO NRs 具有独特的表面积和优异的粒径。本研究还评估了 ZnO NRs 的光催化和抗氧化活性。使用Daniorerio模型分析所得ZnO NRs的毒性，结果表明其无毒。还使用人肺癌细胞系 (A549) 分析了 ZnO NRs 的抗癌活性，并且在癌细胞死亡途径方面观察到了极好的结果。因此，证实所获得的 ZnO NRs 是无毒的，并具有出色的抗菌和抗氧化活性。它们可以用作医疗保健实施的抗癌药物。