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Metabolic Engineering and Synthetic Biology of Cyanobacteria for Carbon Capture and Utilization
Biotechnology and Bioprocess Engineering ( IF 3.2 ) Pub Date : 2020-11-23 , DOI: 10.1007/s12257-019-0447-1
Napisa Pattharaprachayakul , Jong-il Choi , Aran Incharoensakdi , Han Min Woo

Cyanobacteria are photosynthetic bacteria that can directly convert CO2 into several bio-products for industrial use, such as alcohols and diols, terpenes, acids, and sugars. However, some of these compounds are either produced in low amounts or are absent in cyanobacteria, and thus strain development is required to achieve optimal production of these bio-products for industrial applications. Metabolic engineering has been applied to modify cyanobacteria for enhanced production of value-added compounds. In this review, we have elucidated metabolic engineering of various pathways with the yield and productivity of the desired products. We have also described recent overall strategies in advanced metabolic engineering.



中文翻译:

蓝藻的代谢工程与合成生物学,用于碳的捕集与利用

蓝细菌是光合作用细菌,可以将CO 2直接转化为几种工业用途的生物产品,例如醇和二醇,萜烯,酸和糖。然而,这些化合物中的某些要么少量生产,要么在蓝细菌中不存在,因此需要进行菌株开发,以实现工业应用中这些生物产品的最佳生产。代谢工程学已被用于修饰蓝细菌,以提高增值化合物的产量。在这篇综述中,我们阐明了各种途径的代谢工程与所需产物的产量和生产率。我们还描述了高级代谢工程中的最新总体策略。

更新日期:2020-11-25
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