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T 1-mapping and dielectric properties evaluation of a 3D printable rubber-elastomeric polymer as tissue mimicking materials for MRI phantoms
Materials Research Express ( IF 2.3 ) Pub Date : 2020-11-21 , DOI: 10.1088/2053-1591/abc76f
Lotfi Talalwa 1, 2, 3 , Ghaleb Natour 2, 3 , Andreas Bauer 1 , Alexander Drzezga 1, 4 , Ali Gordji-Nejad 1 , Simone Beer 1
Affiliation  

In this study, a new series of 3D printable rubber-elastomeric polymer called PORO-LAY materials have been investigated regarding their suitability to serve as tissue mimicking materials (TMMs) for MRI phantoms. PORO-LAY materials have been previously used in biofuel cell developments, particle filtrations and modeling elastic tissues. We evaluated the electrical permittivity, electrical conductivity, spin-lattice T 1-relaxation time and acquired the MRI contrast for simple and multi-material complex 3D printed shapes made of PORO-LAY materials at 3.0 T. The results showed a T 1 diversity within PORO-LAY materials, which reveals in different MR image contrasts. The outcome favors PORO-LAY as an appropriate candidate that can be used in multi-materials additive manufacturing to produce realistic shapes such as white/grey matter structures for MRI phantoms with visible clear contrast. Finally, this study could serve as a reference and guideline when using these materials as tissue mimicking materials for different types of human body tissues and provide a promising opportunity to design novel phantoms for a wide range of MRI applications.



中文翻译:

作为 MRI 模型的组织模拟材料的 3D 可打印橡胶弹性聚合物的T 1映射和介电性能评估

在这项研究中,研究了一系列新的 3D 可打印橡胶弹性聚合物,称为 PORO-LAY 材料,研究它们作为 MRI 幻影的组织模拟材料 (TMM) 的适用性。PORO-LAY 材料以前曾用于生物燃料电池开发、颗粒过滤和弹性组织建模。我们评估了介电常数、电导率、自旋晶格T 1 -弛豫时间,并在 3.0 T 下获得了由 PORO-LAY 材料制成的简单和多材料复杂 3D 打印形状的 MRI 对比度。结果显示T 1PORO-LAY 材料的多样性,体现在不同的 MR 图像对比度中。结果表明 PORO-LAY 是一种合适的候选材料,可用于多材料增材制造,以产生逼真的形状,例如具有可见清晰对比度的 MRI 幻影的白/灰质结构。最后,当使用这些材料作为不同类型人体组织的组织模拟材料时,这项研究可以作为参考和指南,并为设计用于广泛 MRI 应用的新型体模提供了有希望的机会。

更新日期:2020-11-21
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