Studies on the toxic effects of cooking with aluminum pots are limited and none of them have explored its impact on the genetic material in germ and somatic cells. Therefore, this study investigated the cytogenotoxic effect of boiled water from new, 3- and 6-year old aluminum pots in germ and somatic cells viz-a-vis mouse sperm morphology test and sperm count; and the bone marrow micronucleus test. The mice were allowed to freely drink the boiled water from the different aluminum pots for 3, 4, and 5 weeks. The heavy metal analysis showed that As, Pb, Cd, and Al were present in the boiled water samples at different concentrations with the 6-year old pot having the highest concentrations of Pb, Cd, and Al. There were duration of exposure and age of pot-dependent significant increase in abnormal sperm cells and a significant decrease total mean sperm count of exposed mice. Similarly, there was a statistically significant increase in micronucleated polychromatic erythrocytes and nuclear abnormalities in the exposed mice that increased dependently upon the age of the cookware. Finally there were significantly increased activities of serum AST and ALT; and the liver concentrations of MDA, SOD and CAT in boiled water exposed mice. The findings of this study revealed that boiled water from aluminum pots is capable of inducing cytotoxic and genotoxic effects, especially as the pot ages.

关于用铝锅烹饪的毒性作用的研究是有限的，而且没有人探讨过铝锅对生殖细胞和体细胞遗传物质的影响。因此，本研究调查了来自新的、3 年和 6 年旧铝罐的沸水对生殖细胞和体细胞的细胞遗传毒性作用，即小鼠精子形态学测试和精子计数；和骨髓微核试验。允许小鼠自由饮用不同铝壶中的开水 3、4 和 5 周。重金属分析表明，开水样品中存在不同浓度的 As、Pb、Cd 和 Al，其中 6 年的锅具有最高的 Pb、Cd 和 Al 浓度。暴露的持续时间和罐依赖性异常精子细胞的年龄显着增加，暴露小鼠的总平均精子数显着减少。类似地，暴露的小鼠的微核多染红细胞和核异常在统计学上显着增加，这些增加依赖于炊具的年龄。最后血清AST和ALT活性显着升高；开水暴露小鼠肝脏中MDA、SOD和CAT的浓度。这项研究的结果表明，铝锅中的开水能够引起细胞毒性和基因毒性作用，尤其是随着锅的老化。在暴露的小鼠中，微核多染红细胞和核异常在统计学上显着增加，这些增加依赖于炊具的年龄。最后血清AST和ALT活性显着升高；开水暴露小鼠肝脏中MDA、SOD和CAT的浓度。这项研究的结果表明，铝锅中的开水能够引起细胞毒性和基因毒性作用，尤其是随着锅的老化。在暴露的小鼠中，微核多染红细胞和核异常在统计学上显着增加，这些增加依赖于炊具的年龄。最后血清AST和ALT活性显着升高；开水暴露小鼠肝脏中MDA、SOD和CAT的浓度。这项研究的结果表明，铝锅中的开水能够引起细胞毒性和基因毒性作用，尤其是随着锅的老化。