One-pot synthesis of 2-ethylhexanol(2EHO) from n-butyraldehyde is of commercialimportance. The promotion of 2EHO selectivity requires suppressing direct hydrogenation of n-butyraldehyde. In this work, a series of NiO-MO_x/Nb₂O₅-TiO₂ catalysts were prepared and utilized by means of reduction-in-reaction technique, aiming at delaying the formation of metal sites and suppressing the direct hydrogenation. NiO-MnO₂/Nb₂O₅-TiO₂ with a Ni/Mn mass ratio of 10 and NiO-MnO₂ loading of 14.3 wt% shows the best catalytic performance; 2-EHO selectivity could reach 90.0% at a complete conversion of n-butyraldehyde. Furthermore the catalyst could be used for four times without a substantial change in its catalytic performance.

从正丁醛一锅法合成2-乙基己醇（2EHO）具有商业意义。促进2EHO选择性需要抑制正丁醛的直接氢化。本工作通过还原反应技术制备并利用了一系列NiO-MO _x / Nb ₂ O ₅ -TiO ₂催化剂，旨在延缓金属位点的形成并抑制直接氢化。的NiO-的MnO ₂ / Nb之₂ ö ₅ -TiO ₂为10的镍/ Mn质量比和NiO-的MnO ₂14.3 wt％的负载量显示出最佳的催化性能；在正丁醛完全转化时，2-EHO选择性可以达到90.0％。此外，该催化剂可以使用四次而其催化性能没有实质变化。