Marine bacteria are excellent yet often underexplored sources of structurally unique bioactive natural products. In this review we cover the diversity of marine bacterial biomolecules and highlight recent studies on structurally novel natural products. We include different compound classes and discuss the latest progress related to their biosynthetic pathway analysis and engineering: examples range from fatty acids over terpenes to PKS, NRPS and hybrid PKS–NRPS biomolecules.

中文翻译：

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海洋天然产物生物合成研究的近期亮点

海洋细菌是极好的，但常常是结构独特的生物活性天然产物的未开发来源。在这篇综述中，我们涵盖了海洋细菌生物分子的多样性，并重点介绍了对结构新颖的天然产物的最新研究。我们包括不同的化合物类别，并讨论与其生物合成途径分析和工程相关的最新进展：例子包括从萜烯上的脂肪酸到PKS，NRPS和PKS-NRPS杂交生物分子。