Paclitaxel nanoparticles are a compound with unique anticancer effects. Its mechanism of action is to prevent tumor rupture by stabilizing tumor proteins, while preventing cell division, leading to cell death, thereby inhibiting the spread of lung tumors. This article aims to study the treatment of lung tumors with paclitaxel nanoparticles assisted by tennis rehabilitation training. In this paper, paclitaxel nanoparticles were prepared by a solvent displacement method, and their particle size and morphology were measured. The TA2 series of experimental rats were selected to establish animal lung tumor models, and they were randomly divided into 5 groups: local injection of saline, porphyrin, and low-, medium-, and high-dose paclitaxel nanoparticles for treatment. The experimental results in this paper show that the average particle size of the paclitaxel nanoparticles prepared in the experiment is about 153,54 nm. Each treatment group inhibited tumor development to varying degrees. Among them, the inhibitory volume rate of paclitaxel nanoparticles in the middle- and high-dose groups was significantly higher than that in the paclitaxel treatment group, indicating that paclitaxel nanoparticles can release drugs slowly.

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网球康复训练辅助紫杉醇纳米颗粒治疗肺肿瘤

紫杉醇纳米颗粒是一种具有独特抗癌作用的化合物。其作用机制是通过稳定肿瘤蛋白来防止肿瘤破裂，同时阻止细胞分裂，导致细胞死亡，从而抑制肺部肿瘤的扩散。本文旨在研究网球康复训练辅助紫杉醇纳米粒治疗肺部肿瘤的疗效。本文采用溶剂置换法制备紫杉醇纳米粒，并测定其粒径和形貌。选择TA2系列实验大鼠建立动物肺肿瘤模型，随机分为5组：局部注射生理盐水、卟啉、低、中、高剂量紫杉醇纳米粒进行治疗。本文的实验结果表明，实验中制备的紫杉醇纳米粒子的平均粒径约为153.54 nm。每个治疗组都不同程度地抑制了肿瘤的发展。其中，中、高剂量组紫杉醇纳米粒的抑制体积率明显高于紫杉醇治疗组，说明紫杉醇纳米粒可以缓慢释放药物。