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3D Biofabrication Using Living Cells for Applications in Biohybrid Sensors and Actuators
ACS Applied Bio Materials ( IF 4.7 ) Pub Date : 2020-11-19 , DOI: 10.1021/acsabm.0c01214
Minghao Nie 1 , Shoji Takeuchi 1, 2, 3, 4
Affiliation  

In this paper, we highlight the concept of biohybrid sensors and actuators built by incorporating living cells into artificial systems. Instead of using the materials extracted from cells, these approaches utilize cells to dynamically generate functional materials and to provide the native intracellular environment for the proper functioning of the materials. By incorporating the functional cells into artificial devices/chips, the cell-based biohybrid approaches can be applied to create portable odorant sensors with high sensitivity and to create biohybrid muscle actuators for applications in both drug screening and soft robotics.

中文翻译:

使用活细胞的 3D 生物制造在生物混合传感器和执行器中的应用

在本文中,我们强调了通过将活细胞整合到人工系统中构建的生物混合传感器和执行器的概念。这些方法不是使用从细胞中提取的材料,而是利用细胞动态生成功能材料并为材料的正常功能提供天然的细胞内环境。通过将功能性细胞整合到人工设备/芯片中,基于细胞的生物混合方法可用于创建具有高灵敏度的便携式气味传感器,并创建用于药物筛选和软机器人应用的生物混合肌肉执行器。
更新日期:2020-12-21
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