Dehydrogenases dependent on NAD(P)H are widely applied for biosynthesis of chiral chemicals. However, they are unstable and easy denaturated compared with hydrolases. A new strategy for dehydrogenases immobilization with the advantages of easy operation and high activity recovery should be developed. Biocompatible hybrid materials (GO‐PEI‐M) have been obtained by metal ions coordinated polyethylenimine (PEI) functionalized graphene oxide (GO).

中文翻译：

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金属离子通过GO-PEI协同固定苯丙氨酸脱氢酶，具有高活性回收率和增强的稳定性

依赖于NAD（P）H的脱氢酶被广泛用于手性化学品的生物合成。但是，与水解酶相比，它们不稳定并且容易变性。应该开发一种具有易于操作和高活性回收的优点的固定脱氢酶的新策略。生物相容性杂化材料（GO‐PEI‐M）是通过金属离子配位的聚乙烯亚胺（PEI）功能化的氧化石墨烯（GO）获得的。