当前位置: X-MOL 学术IUBMB Life › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Inhibited histone deacetylase 3 ameliorates myocardial ischemia–reperfusion injury in a rat model by elevating microRNA ‐19a‐3p and reducing cyclin‐dependent kinase 2
IUBMB Life ( IF 4.6 ) Pub Date : 2020-11-20 , DOI: 10.1002/iub.2402
Kaiyou Song 1 , Lianting Li 2 , Qingqing Quan 3 , Yanjin Wei 1 , Shunpeng Hu 1
Affiliation  

Over the years, the roles of microRNAs (miRNAs) and histone deacetylase 3 (HDAC3) in human diseases have been investigated. This study focused on the effect of miR‐19a‐3p and HDAC3 in myocardial ischemia–reperfusion (I/R) injury (MIRI) by targeting cyclin‐dependent kinase 2 (CDK2).

中文翻译:

抑制组蛋白去乙酰化酶 3 通过提高 microRNA ‐19a‐3p 和减少细胞周期蛋白依赖性激酶 2 来改善大鼠模型中的心肌缺血再灌注损伤

多年来,人们一直在研究微 RNA (miRNA) 和组蛋白去乙酰化酶 3 (HDAC3) 在人类疾病中的作用。本研究通过靶向细胞周期蛋白依赖性激酶 2 (CDK2) 来研究 miR-19a-3p 和 HDAC3 在心肌缺血再灌注 (I/R) 损伤 (MIRI) 中的作用。
更新日期:2020-11-20
down
wechat
bug