The antiproliferative activity of 6-substituted polycarbonitrile derivatives of 3-azabicyclo[3.1.0]hexane was studied. It was established that the activity of the substances was directly related to the presence of a 6-substituent. Thus, 6-substituted derivatives of 3-azabicyclo[3.1.0]hexane did not possess antiproliferative activity and could be of interest only as potential antitussive and hypoglycemic drugs.

中文翻译：

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3-氮杂双环[3.1.0]己烷的6-取代聚腈衍生物中缺少抗增殖活性

研究了3-氮杂双环[3.1.0]己烷的6-取代聚腈衍生物的抗增殖活性。已确定物质的活性与 6-取代基的存在直接相关。因此，3-氮杂双环[3.1.0] 己烷的 6-取代衍生物不具有抗增殖活性，只能作为潜在的镇咳和降血糖药物而受到关注。