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Phenotype and biological characteristics of endometrial mesenchymal stem/stromal cells: A comparison between intrauterine adhesion patients and healthy women
American Journal of Reproductive Immunology ( IF 3.6 ) Pub Date : 2020-11-18 , DOI: 10.1111/aji.13379
Jiali Min 1 , Na Lu 2 , Shengjian Huang 3 , Xiahua Chai 1 , Susu Wang 1 , Lin Peng 4, 5 , Jian Wang 1, 2, 3
Affiliation  

Intrauterine adhesion (IUA) is a uterine disorder with partial or total obstruction of the uterine cavity and/or the cervical canal primarily caused by intrauterine operations and infections. It is the most common cause of uterine infertility and recurrent abortion. However, the reasons for endometrium repair disorders in patients with IUA are still unclear. While increasing evidence demonstrates that endometrial mesenchymal stem/stromal cells (EMSCs) contribute to the regeneration and repair of endometrium, the roles of EMSCs in the pathogenesis of IUA have not been reported.

中文翻译:

子宫内膜间充质干/间质细胞的表型和生物学特征:宫腔粘连患者与健康女性的比较

宫腔粘连(IUA)是一种主要由宫腔内手术和感染引起的子宫腔和/或宫颈管部分或全部阻塞的子宫疾病。它是子宫不孕和反复流产的最常见原因。然而,IUA患者子宫内膜修复障碍的原因尚不清楚。虽然越来越多的证据表明子宫内膜间充质干/基质细胞 (EMSCs) 有助于子宫内膜的再生和修复,但尚未报道 EMSCs 在 IUA 发病机制中的作用。
更新日期:2020-11-18
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