Since the early 1990s asymmetric catalytic applications of chiral, azetidine-derived, ligands and organocatalysts have been developed and utilised to engender asymmetry in reactions including Friedel-Crafts alkylations, Henry reactions and Michael-type reactions. This review surveys the effective synthetic opportunities presented by chiral azetidines in asymmetric catalysis. In order to benchmark, contrast and evaluate these asymmetric azetidine-containing catalysts, comparisons with aziridine- and pyrrolidine-containing analogues are drawn.

中文翻译：

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氮杂环丁烷及其在不对称催化中的应用

自1990年代初以来，已开发并利用手性，氮杂环丁烷衍生的配体和有机催化剂的不对称催化应用，并使其在包括Friedel-Crafts烷基化，Henry反应和Michael型反应在内的反应中引起不对称。这篇综述调查了不对称催化中手性氮杂环丁烷所提供的有效合成机会。为了进行基准测试，对比和评估这些不对称的含氮杂环丁烷的催化剂，与含氮丙啶和吡咯烷的类似物进行了比较。