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ICEHpsaHPS7, a Novel Multiple Drug Resistance Integrative Conjugative Element in Glaesserella parasuis
Antimicrobial Agents and Chemotherapy ( IF 4.9 ) Pub Date : 2021-01-20 , DOI: 10.1128/aac.01716-20
Jiahui An 1, 2 , Genglin Guo 1, 2, 3 , Dong Yu 1, 2 , Kexin Zhu 1, 2 , Chao Zhang 1, 2 , Yufeng Li 2, 4
Affiliation  

Integrative conjugative elements (ICEs) are a kind of novel self-transmissible mobile genetic element. In this study, a novel ICE was identified in Glaesserella (Haemophilus) parasuis. We confirmed that it could mediate the migration of antimicrobial resistance genes in G. parasuis and found that there may have been a transferring potential between different serovar strains of G. parasuis. These findings demonstrate that the ICE is crucial to the horizontal transfer of antimicrobial resistance among G. parasuis strains.

中文翻译:

ICEHpsaHPS7,一种副猪Glaesserella的新型多重耐药整合共轭元件

整合共轭元件(ICEs)是一种新型的自我传播的移动遗传元件。在这项研究中,一种新型的ICE中被鉴定Glaesserella嗜血副猪嗜血杆菌。我们证实,它可介导抗生素抗性基因的迁移G.副猪嗜血杆菌,发现有可能是不同的血清型菌株之间的转移潜能G.副猪嗜血杆菌。这些发现表明,ICE对于副猪嗜热菌菌株之间的抗药性水平转移至关重要。
更新日期:2021-01-20
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