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Compound‐specific sulfur isotope analysis of cysteine and methionine via preparatory liquid chromatography and elemental analyzer isotope‐ratio mass spectrometry
Rapid Communications in Mass Spectrometry ( IF 2 ) Pub Date : 2020-11-17 , DOI: 10.1002/rcm.9007
Alexandra A. Phillips 1 , Fenfang Wu 1 , Alex L. Sessions 1
Affiliation  

Compound‐specific isotope analysis (CSIA) of organic sulfur molecules has previously been hindered by challenging preparatory chemistry and analytical requirements for large sample sizes. The natural‐abundance sulfur isotopic compositions of the sulfur‐containing amino acids, cysteine and methionine, have therefore not yet been investigated despite potential utility in biomedicine, ecology, oceanography, biogeochemistry, and other fields.

中文翻译:

通过制备型液相色谱和元素分析仪同位素比质谱法分析半胱氨酸和蛋氨酸的化合物特异性硫同位素

以前,挑战性的制备化学和大样本量的分析要求阻碍了有机硫分子的化合物特异性同位素分析(CSIA)。尽管具有潜在的生物医学,生态学,海洋学,生物地球化学和其他领域的用途,但尚未研究含硫氨基酸,半胱氨酸和蛋氨酸的天然丰度硫同位素组成。
更新日期:2020-11-17
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