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Smart nanotheranostic hydrogels for on-demand cancer management
Drug Discovery Today ( IF 7.4 ) Pub Date : 2020-11-17 , DOI: 10.1016/j.drudis.2020.11.010
Ranjita Misra 1 , Sarbari Acharya 2
Affiliation  

Much research effort has been dedicated to unveiling the complexity of tumors for the development of effective treatment approaches. The idea of applying nanotheranostics for cancer management has transcended from a ‘hype to hope’ scenario. Furthermore, use of engineered hydrogels containing nanotheranostics has paved the path for generating smart cargos for effective diagnosis and remission. Hydrogels, used as reservoirs for smart nanotheranostics, facilitate the sustained release of drugs and imaging agents for a prolonged period of time, thereby assisting in early disease diagnosis, therapy, and prognosis. In this review, we discuss the use of engineered hydrogels as biomedical theranostic agents.



中文翻译:

用于按需癌症管理的智能纳米治疗水凝胶

许多研究工作致力于揭示肿瘤的复杂性,以开发有效的治疗方法。将纳米治疗学应用于癌症管理的想法已经超越了“炒作到希望”的情景。此外,使用含有纳米治疗学的工程水凝胶为生成用于有效诊断和缓解的智能货物铺平了道路。水凝胶用作智能纳米治疗学的储库,可促进药物和显像剂的长时间持续释放,从而有助于疾病的早期诊断、治疗和预后。在这篇综述中,我们讨论了工程水凝胶作为生物医学治疗诊断剂的用途。

更新日期:2020-11-17
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