In this study, a practical and excellent method was used to determine the famoxadone and cymoxanil via high-performance liquid chromatography equipped utilizing ultraviolet detector lamp (HPLC-UV) for investigating the dissipation behavior and residue distribution of famoxadone and cymoxanil in cucumber and soil ecosystem. The limit of quantification (LOQ_S) of famoxadone and cymoxanil in cucumber were 0.50, 1.00, 2.00 and 0.05, 0.50, 1.00 mg kg⁻¹ in soil, respectively. The limit of detection (LOD_S) of both famoxadone and cymoxanil were 8.0 ng. The average recoveries (n = 5) of the fungicide ranged from 84.10 to 108.02% with the relative standard deviations (RSDs) typically < 9.23%. The fungicide was applied to cucumber and soil at the range of doses (275.6–413.4 g a.i.ha⁻¹) three or four times. The half-lives of famoxadone and cymoxanil in cucumber and soil were 1.34–16.12 days, which followed the first-order chemical reaction kinetics equation C_t = C₀ × e^-kt. The residues of famoxadone and cymoxanil in cucumber at the pre-harvest interval (PHI, 3 days) were below 8.0 × 10⁻⁸ g and 8.0 × 10⁻⁹ g, respectively. Overall, this study evaluated the food safety and the environmental fate of famoxadone and cymoxanil in cucumber and soil ecosystem. In addition, this study would promote the series of work on the pesticide exposure assessment of these fungicides as well.

在这项研究中，采用一种实用且优异的方法，通过配备紫外检测灯（HPLC-UV）的高效液相色谱法，测定法莫沙酮和苯并恶草胺在黄瓜和土壤生态系统中的消散行为和残留物分布，从而测定法莫沙酮和邻苯二酚的残留量。 。在土壤中，法莫沙酮和头孢克肟的定量限（LOQ _S）分别为0.50、1.00、2.00和0.05、0.50、1.00mg kg ^-1。Famoxadone和Cymoxanil的检出限（LOD _S）为8.0 ng。平均回收率（n = 5）的杀菌剂含量在84.10％至108.02％之间，相对标准偏差（RSD）通常<9.23％。该杀真菌剂以三到四次的剂量范围（275.6–413.4 g aiha ^-1）施用于黄瓜和土壤。法莫沙酮和头孢克肟在黄瓜和土壤中的半衰期为1.34–16.12天，遵循一阶化学反应动力学方程C _t  =  C ₀  ×  e ^-kt。黄瓜在收获前间隔（PHI，3天）的残留量分别低于8.0×10 ^-8  g和8.0×10 ^-9 g，分别。总体而言，本研究评估了黄瓜和土壤生态系统中的法莫沙酮和环草胺的食品安全性和环境命运。此外，这项研究还将促进对这些杀菌剂的农药暴露评估的一系列工作。