Renal cell carcinoma (RCC) is a common malignant tumor that seriously endangers people's health. In recent years, long non-coding RNAs (lncRNAs) have been discovered to play vital roles in diverse cancers, including RCC. LncRNA lysyl oxidase like 1 antisense RNA 1 (LOXL1-AS1) has been found to exert carcinogenic functions in several cancers, but its role and mechanism in RCC have not been investigated.

中文翻译：

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较长的无末端RNA LOXL1-AS1使miR-589-5p上调在肾细胞癌中的CBX5表达。

肾细胞癌（RCC）是一种常见的恶性肿瘤，严重危害人们的健康。近年来，已发现长的非编码RNA（lncRNA）在包括RCC在内的多种癌症中起着至关重要的作用。已经发现LncRNA赖氨酰氧化酶（如1反义RNA 1（LOXL1-AS1））在多种癌症中均具有致癌作用，但尚未研究其在RCC中的作用和机制。