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Assessing keloid recurrence following surgical excision and radiation
Burns & Trauma ( IF 5.3 ) Pub Date : 2020-11-14 , DOI: 10.1093/burnst/tkaa031
Michael H Gold 1 , Mark S Nestor 2 , Brian Berman 3 , David Goldberg 4
Affiliation  

Keloids are a fibroproliferative disorder that can result from a cutaneous injury to the reticular dermis. Recurrence rates as high as 100% have been reported following surgical excision alone. Consequently, a variety of post-surgical techniques have been employed to prevent keloid recurrence, including the use of radiation. Although numerous studies have shown post-excisional X-rays, electron beam, lasers and brachytherapy can reduce the rate of keloid recurrence, numerous inconsistencies, including a wide range of definitions for keloid recurrence, make it difficult to compare study outcomes. The review aims to examine the various means for defining keloid recurrence in clinical trials involving the use of radiation therapy.

中文翻译:

手术切除和放射后评估瘢痕loid复发

瘢痕loid是一种纤维增生性疾病,可能是由于网状真皮的皮肤损伤所致。单纯手术切除后复发率高达100%。因此,已经采用了多种外科手术后技术来防止瘢痕loid复发,包括使用放射线。尽管大量研究表明,切除后的X射线,电子束,激光和近距离放射治疗可以降低瘢痕loid复发率,但许多不一致之处,包括范围广泛的瘢痕loid复发定义,使比较研究结果变得困难。该综述旨在研究在涉及放射治疗的临床试验中定义瘢痕loid复发的各种方法。
更新日期:2020-11-16
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