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Design of an endomicroscope including a resonant fiber-based microprobe dedicated to endoscopic polarimetric imaging for medical diagnosis
Biomedical Optics Express ( IF 3.4 ) Pub Date : 2020-11-10 , DOI: 10.1364/boe.403157
Colman Buckley , Marc Fabert , Damien Kinet , Vytautas Kucikas , Dominique Pagnoux

We report on a novel endomicroscope, to the best of our knowledge, designed for achieving full 4×4 Mueller polarimetric images of biological tissues through a fiber endoscope for medical diagnosis. The polarimetric technique is based on a previously published two-wavelength differential method (TWDM). A key component of the endomicroscope is a resonant fiber-based microprobe including a highly-selective fiber Bragg grating (FBG), free of detrimental polarimetric effects, photo written in the core of the fiber, near the output face. By means of the TWDM, and using the specially designed microprobe (diameter 2.9 mm, length 30 mm), full Mueller images of 250×250 pixels were produced at the rate of 1 image/2 s through a 2 m single mode fiber, paving the way to in vivo applications in polarimetric endomicroscopy.

中文翻译:

内窥镜的设计,包括基于共振光纤的微探针,用于医学诊断的内窥镜偏振成像

据我们所知,我们报告了一种新型内窥镜,旨在通过用于医疗诊断的纤维内窥镜获得生物组织的完整4×4 Mueller偏振图像。极化技术基于先前发布的两波长差分方法(TWDM)。内窥镜的关键组件是基于共振光纤的微探针,包括一个高选择性的光纤布拉格光栅(FBG),该光栅没有有害的偏振效应,照片写在光纤的核心中,靠近输出面。通过TWDM,并使用经过特殊设计的微探针(直径2.9 mm,长度30 mm),通过2 m单模光纤以1图像/ 2 s的速率产生250×250像素的完整Mueller图像,偏振内窥镜体内应用的方式。
更新日期:2020-12-01
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