Organic azides are highly reactive, which have long established as versatile building blocks in the assembly of structurally diverse N‐containing heterocycles. The conversion of organic azides into high‐value compounds is of great importance and a subject of enormous current interest. Transition metal‐catalyzed C(sp²)−H amination/annulation of organic azides provides a powerful tool for the transformation of organic azides into a wide range of biologically important heterocyclic frameworks. In this review, we aim to summarize the recent progress on organic azides‐mediated C(sp²)−H amination/annulation for N‐heterocycle synthesis enabled by transition metal catalysts. Representative strategies are discussed in detail, including catalytic systems, reaction scopes, limitations and mechanisms.

中文翻译：

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有机叠氮化物：过渡金属催化的C（sp2）-H胺化/环化反应的多功能合成子，用于N-杂环合成

有机叠氮化物具有很高的反应活性，长期以来在结构多样的含氮杂环化合物的组装中已确立了其多功能性。有机叠氮化物向高价值化合物的转化非常重要，也是当前引起人们极大兴趣的主题。过渡金属催化的有机叠氮化物的C（sp ²）-H胺化/环化为有机叠氮化物转化为多种生物学上重要的杂环骨架提供了强大的工具。在这篇综述中，我们旨在总结有机叠氮化物介导的C（sp ²（H）氨基化/环化反应，可通过过渡金属催化剂进行N杂环合成。详细讨论了代表性策略，包括催化体系，反应范围，局限性和机理。