A carbon paste electrode (CPE) modified with Nafion, Graphene oxide and zeolite has been prepared and characterized, and the resulting Nafion/Graphene oxide/Zeolite modified carbon paste electrode (N/G/Z/MCPE) has been applied to the electrochemical detection of Moxifloxacin hydrochloride (MOXI). It exhibited a good electrocatalytic activity in phosphate buffer (optimum at pH 7.4), as pointed out by cyclic voltammetry (CV), and N/G/Z/MCPE can be exploited for MOXI detection by chronoamperometry, electrochemical impedance spectroscopy and differential pulse voltammetry. This latter was the most sensitive one and gave rise to a linear calibration curve in the 0.04 to 250 μM concentration range, with limits of detection and qualification estimated at 1.0 nM and 3.3 nM, respectively. Contrary to previous electrochemical sensors for MOXI (e. g., CPE modified with metal nanoparticles), this new sensor can be used for multiple successive analyses without needing to refresh its surface.

中文翻译：

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基于Nafion /氧化石墨烯/沸石修饰的碳糊电极的盐酸莫西沙星敏感电化学传感器

制备并表征了用Nafion，氧化石墨烯和沸石改性的碳糊电极（CPE），并将所得的Nafion /氧化石墨烯/沸石改性的碳糊电极（N / G / Z / MCPE）用于电化学检测盐酸莫西沙星（MOXI）。正如循环伏安法（CV）所指出的那样，它在磷酸盐缓冲液中具有良好的电催化活性（最适pH值为7.4），N / G / Z / MCPE可以通过计时安培法，电化学阻抗谱和差分脉冲伏安法用于MOXI检测。 。后者是最敏感的一个，在0.04至250μM浓度范围内产生线性校准曲线，估计的检出限和鉴定限分别为1.0 nM和3.3 nM。与以前的MOXI电化学传感器相反（例如，