An alternative route to the synthesis of N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxy ethyl)piperazin-1-yl)-2-methyl pyrimidin-4-yl)amino)thiazole-5-carboxamide,Chemical Data Collections

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An alternative route to the synthesis of N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxy ethyl)piperazin-1-yl)-2-methyl pyrimidin-4-yl)amino)thiazole-5-carboxamide
Chemical Data Collections Pub Date : 2021-02-01 , DOI: 10.1016/j.cdc.2020.100590
Shaik Shahinshavali , K. Deepti , Suryadevara Vijayavardhini , Abbaraju Venkata Durga Nagendra Kumar , Reddymasu Sireesha , S. Pulla Reddy , M.V. Basaveswara Rao

Abstract The target compound, N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl) piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide can be achieved by coupling between 2-bromo-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide and 2-(4-(6-amino-2-methylpyrimidin-4-yl)piperazin-1-yl)ethan-1-ol.

中文翻译：

合成 N-(2-氯-6-甲基苯基)-2-((6-(4-(2-羟基乙基)哌嗪-1-基)-2-甲基嘧啶-4-基)的另一种途径)氨基)噻唑-5-甲酰胺

摘要目标化合物N-(2-氯-6-甲基苯基)-2-((6-(4-(2-羟乙基)哌嗪-1-基)-2-甲基嘧啶-4-基)氨基)噻唑- 5-甲酰胺可以通过2-溴-N-(2-氯-6-甲基苯基)噻唑-5-甲酰胺和2-(4-(6-氨基-2-甲基嘧啶-4-基)哌嗪- 1-yl)ethan-1-ol。

更新日期：2021-02-01

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