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Dosimetry for New Radiation Therapy Approaches Using High Energy Electron Accelerators
Frontiers in Physics ( IF 3.1 ) Pub Date : 2020-09-28 , DOI: 10.3389/fphy.2020.568302
Karolina Kokurewicz , Andreas Schüller , Enrico Brunetti , Anna Subiel , Rafael Kranzer , Thomas Hackel , Markus Meier , Ralf-Peter Kapsch , Dino A. Jaroszynski

We have performed dosimetry studies using electron beams with energies up to 50 MeV, which exceed current clinical energy ranges and approaches the bottom end of the very high energy electron range. 50 MeV electron beams can reach deep-seated tumors. In contrast to photon beams, electron beams can be generated with ultra-high dose rates by linear accelerators, which could enable FLASH radiotherapy of deep-seated tumors. The response of radiochromic film and alanine is compared with dose measurements using an ionisation chamber. Energy dependence is not observed within the measurement uncertainty in the investigated energy range from 15 to 50 MeV.



中文翻译:

使用高能电子促进剂的新型放射治疗方法的剂量测定

我们已经使用能量高达50 MeV的电子束进行了剂量学研究,该能量超过了当前的临床能量范围,并接近了非常高能量的电子范围的底端。50 MeV电子束可以到达根深蒂固的肿瘤。与光子束相反,可以通过线性加速器以超高剂量率产生电子束,这可以实现对深部肿瘤的FLASH放射疗法。使用电离室将放射变色膜和丙氨酸的响应与剂量测量进行比较。在研究的15至50 MeV的能量范围内,在测量不确定度内未观察到能量依赖性。

更新日期:2020-11-13
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