In this work, a novel design of Zinc Oxide (ZnO) and bi-metallic (Ag–Au) layers based surface plasmon resonance (SPR) biosensor with barium titanate (BaTiO₃) and graphene is proposed. The proposed structure consists of SF10 glass prism, ZnO, Ag, Au, BaTiO₃, and graphene as a top layer for biomolecules adsorption. Here, the performance of this structure is studied and analysed for sensitivity along with the accuracy of detection and quality parameter for the shift in refractive index (RI) from 1.33 (sensing medium) to 1.45 and our reported results show that addition of bimetallic (Ag–Au) layers along with BaTiO₃, improve the sensitivity of the proposed structure to 14.85% for the same RI range compared to last reported MoS₂-graphene-based SPR sensor. Here at $\lambda =632.8\text{nm},$ maximum sensitivity is reported as 116.67 degree/RIU while the accuracy of detection and the quality parameter are obtained as 4.54 and 37.87 RIU⁻¹ respectively. These high-performance parameters of the design make this structure suitable for biosensing applications.

在这项工作中，提出了一种基于钛酸钡 (BaTiO ₃ ) 和石墨烯的氧化锌 (ZnO) 和双金属 (Ag–Au) 层表面等离子共振 (SPR) 生物传感器的新颖设计。_{所提出的结构由 SF10 玻璃棱镜、ZnO、Ag、Au、BaTiO 3}和作为生物分子吸附顶层的石墨烯组成。在这里，针对折射率 (RI) 从 1.33（传感介质）到 1.45 的变化，研究和分析了该结构的灵敏度以及检测精度和质量参数的性能，我们报告的结果表明，添加双金属（Ag –Au) 层连同 BaTiO ₃，与上次报告的 MoS _{2相比，对于相同的 RI 范围，将所提出结构的灵敏度提高到 14.85%}- 基于石墨烯的 SPR 传感器。在这里$\lambda =632.8\text{纳米},$最大灵敏度报告为 116.67 度/RIU，而检测精度和质量参数分别为 4.54 和 37.87 RIU ^-1。设计的这些高性能参数使这种结构适用于生物传感应用。