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Increased IL‐10‐producing regulatory T cells are characteristic of severe cases of COVID‐19
Clinical & Translational Immunology ( IF 5.8 ) Pub Date : 2020-11-13 , DOI: 10.1002/cti2.1204
Julika Neumann 1, 2 , Teresa Prezzemolo 1, 2 , Lore Vanderbeke 2, 3 , Carlos P Roca 4 , Margaux Gerbaux 2, 5 , Silke Janssens 1, 2 , Mathijs Willemsen 1, 2 , Oliver Burton 4 , Pierre Van Mol 3, 6 , Yannick Van Herck 3 , , Joost Wauters 3 , Els Wauters 3 , Adrian Liston 1, 2, 4 , Stephanie Humblet-Baron 2
Affiliation  

The pandemic spread of the coronavirus SARS‐CoV‐2 is due, in part, to the immunological properties of the host–virus interaction. The clinical presentation varies from individual to individual, with asymptomatic carriers, mild‐to‐moderate‐presenting patients and severely affected patients. Variation in immune response to SARS‐CoV‐2 may underlie this clinical variation.

中文翻译:

产生 IL-10 的调节性 T 细胞增加是 COVID-19 重症病例的特征

冠状病毒 SARS-CoV-2 的大流行性传播部分是由于宿主-病毒相互作用的免疫学特性。临床表现因人而异,有无症状携带者、轻度至中度表现患者和重度患者。对 SARS-CoV-2 的免疫反应的变化可能是这种临床变异的基础。
更新日期:2020-11-13
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