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Annual banned‐substance review: Analytical approaches in human sports drug testing 2019/2020
Drug Testing and Analysis ( IF 2.9 ) Pub Date : 2020-11-12 , DOI: 10.1002/dta.2969
Mario Thevis 1, 2 , Tiia Kuuranne 3 , Hans Geyer 1, 2
Affiliation  

Analytical chemistry‐based research in sports drug testing has been a dynamic endeavor for several decades, with technology‐driven innovations continuously contributing to significant improvements in various regards including analytical sensitivity, comprehensiveness of target analytes, differentiation of natural/endogenous substances from structurally identical but synthetically derived compounds, assessment of alternative matrices for doping control purposes, and so forth. The resulting breadth of tools being investigated and developed by anti‐doping researchers has allowed to substantially improve anti‐doping programs and data interpretation in general. Additionally, these outcomes have been an extremely valuable pledge for routine doping controls during the unprecedented global health crisis that severely affected established sports drug testing strategies. In this edition of the annual banned‐substance review, literature on recent developments in anti‐doping published between October 2019 and September 2020 is summarized and discussed, particularly focusing on human doping controls and potential applications of new testing strategies to substances and methods of doping specified the World Anti‐Doping Agency's 2020 Prohibited List.

中文翻译:

年度禁用物质审查:2019/2020 年人体运动药物测试的分析方法

几十年来,基于分析化学的运动药物检测研究一直是一项充满活力的努力,技术驱动的创新不断促进各方面的显着改进,包括分析灵敏度、目标分析物的全面性、将天然/内源性物质与结构相同但结构相同的物质区分开来。合成衍生化合物,用于兴奋剂控制目的的替代基质的评估等。反兴奋剂研究人员正在研究和开发的工具范围广泛,从而大大改善了反兴奋剂计划和总体数据解释。此外,在史无前例的全球健康危机严重影响了既定的运动药物检测策略期间,这些结果是对常规兴奋剂控制做出的极其宝贵的承诺。在本期年度禁用物质审查,总结和讨论了 2019 年 10 月至 2020 年 9 月期间出版的关于反兴奋剂最新发展的文献,特别关注人体兴奋剂控制以及新的检测策略对物质和兴奋剂方法的潜在应用。兴奋剂机构 2020 年禁用清单。
更新日期:2021-01-18
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