当前位置: X-MOL 学术J. Fish Dis. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Cost‐effectiveness of longitudinal surveillance for Piscirickettsia salmonis using qPCR in Atlantic salmon farms (Salmo salar) in Chile
Journal of Fish Diseases ( IF 2.5 ) Pub Date : 2020-11-12 , DOI: 10.1111/jfd.13285
Marina K. V. C. Delphino 1 , Fernando O. Mardones 2 , Joaquin Neumann Heise 2 , Alicia Gallardo 3 , Daniel Jimenez 4 , Andrea Peña 5 , Marco Rozas‐Serri 5 , Ian A. Gardner 1
Affiliation  

Costs of diagnostic testing including sample collection, sampling frequency and sample size are an important consideration in the evaluation of the economic feasibility of alternative surveillance strategies for detection of infectious diseases in aquatic animals. In Chile, Piscirickettsia salmonis is the primary reason for antibiotic treatments in farmed Atlantic salmon. In 2012, a surveillance and control programme for piscirickettsiosis was established with an overall goal of reducing antibiotic use. The present study estimated the cost‐effectiveness of different sampling frequencies and sample sizes to achieve at least 95% confidence of early detection of P. salmonis at the netpen and farm levels using a validated qPCR test. We developed a stochastic model that incorporated variability in test accuracy, within‐pen prevalence and sampling costs. Our findings indicated that the current piscirickettsiosis surveillance programme based on risk‐based sampling of five moribund or dead fish from 2 to 3 netpens is cost‐effective and gives a high probability of detection of P. salmonis in Atlantic salmon farms in Chile at both the netpen and farm levels. Results from this study should incentivize salmon farmers to establish cost‐effective strategies for early detection of P. salmonis infection and the application of this approach to other highly infectious diseases.

中文翻译:

使用qPCR在智利大西洋鲑鱼养殖场(Salmo salar)进行鲑鱼立克次氏体纵向监测的成本效益

诊断测试的成本(包括样品收集,采样频率和样品量)是评估替代监测策略用于检测水生动物传染病的经济可行性的重要考虑因素。在智利,鲑鱼皮立克次体是养殖大西洋鲑鱼中抗生素治疗的主要原因。2012年,制定了一项针对男子立克次体病的监视和控制计划,其总体目标是减少抗生素的使用。本研究估算了不同采样频率和样本量的成本效益,以实现至少95%的早期检测鲑鱼假单胞菌的置信度在Netpen和农场级别使用已验证的qPCR测试。我们开发了一种随机模型,该模型将测试准确性,笔内流行率和抽样成本的可变性纳入考虑范围。我们的研究结果表明,目前的立克次体病监测计划基于从2到3个网眼的5条垂死或死鱼的基于风险的抽样,是具有成本效益的,并且在智利的两个大西洋鲑鱼养殖场中检出鲑鱼的可能性很高 Netpen和农场级别。这项研究的结果应激励鲑鱼养殖者建立具有成本效益的策略,以及早发现鲑鱼对虾的感染并将这种方法应用于其他高度传染性疾病。
更新日期:2020-11-12
down
wechat
bug