Driven by the continuous demand for sustainable organic synthesis, the field of photocatalysis has emerged as a powerful manifold for direct modification of various chemical compounds. Organic chlorides have not been typically considered as attractive synthetic precursors for these reactions due to their chemical inertness, however, this situation is now rapidly changing. The past five years have witnessed a growing interest in exploring organic chlorides as cheap, readily available and bench-stable substrates for photocatalytic transformations and a number of protocols have already been reported. This Review Article summarises the conceptual ideas behind the developed methods and presents them in the form of synthetic strategies based on how light energy is accumulated in the catalytic system or the way bond energy in the substrate is reduced. The synthetic application of each strategy is also discussed.

在对可持续有机合成的持续需求的推动下，光催化领域已经成为直接修饰各种化合物的强大方法。由于有机氯化物的化学惰性，通常不认为它们是有吸引力的合成前体，然而，这种情况现在正在迅速改变。在过去五年中，目睹了对开发有机氯化物的兴趣日益浓厚，这种廉价，易于获得且稳定的用于光催化转化的底物已经被报道，并且已经报道了许多方案。这篇综述文章总结了所开发方法背后的概念，并以合成策略的形式提出了这些概念，这些策略基于光能如何在催化系统中积累或减少基体中键能的方式。