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An account of synthetic strategies towards indolocarbazole alkaloids: Arcyriaflavin A and staurosporinone
Tetrahedron ( IF 2.1 ) Pub Date : 2020-11-12 , DOI: 10.1016/j.tet.2020.131756
Prajesh Volvoikar , Prachi Torney

An account of synthetic methods developed for indolocarbazole alkaloids arcyriaflavin A and staurosporinone is presented. Based on a common pathway or key intermediate involved, all these methods are broadly grouped into four categories: 1) using bisindolyl maleimide/anhydride, 2) from bisindoles, 3) using Fischer indolisation, 4) involving nitrene insertion. This review discusses in detail the strategies involved in the construction of these two molecules.



中文翻译:

吲哚并咔唑生物碱的合成策略的说明:阿卡曲黄素A和星形孢菌素

介绍了为吲哚并咔唑生物碱阿奇黄素A和星形孢菌素开发的合成方法。基于所涉及的常见途径或关键中间体,所有这些方法大致分为四类:1)使用双吲哚基马来酰亚胺/酸酐; 2)来自双吲哚; 3)使用费歇尔吲哚化法; 4)涉及腈插入。这篇综述详细讨论了这两个分子的构建所涉及的策略。

更新日期:2020-11-12
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