当前位置: X-MOL 学术Front. Vet. Sci. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Herd-Level Risk Factors for Swine Influenza (H1N1) Seropositivity in West Java and Banten Provinces of Indonesia (2016–2017)
Frontiers in Veterinary Science ( IF 3.2 ) Pub Date : 2020-09-22 , DOI: 10.3389/fvets.2020.544279
Nurhayati , Hendra Wibawa , Trian Mahawan , Farida Camallia Zenal , Luuk Schoonman , Caitlin Nicole Pfeiffer , Mark Stevenson , Veerasak Punyapornwithaya

Swine could play a role as a “mixing vessel” for avian and human influenza viruses and should, therefore, be thought of playing an intermediate role in the emergence of pandemic influenza strains. The aim of this study was to identify risk factors for Swine influenza virus (SIV) seropositivity at the farm level in West Java and Banten provinces, Indonesia. A total of 649 blood samples were collected from 175 pig farms, and at the time of sampling, a questionnaire about routine herd management was administered to participant herd managers. Swine influenza virus serological status for each of the sampled pigs was tested using the IDEXX ELISA-test (Maine, US). The apparent herd-level prevalence of SIV seropositivity was expressed as a true herd-level prevalence using the Rogan and Gladen method, modified to account for low and high prevalence herds using a Markov chain Monte Carlo Bayesian approach. The association between herd-level characteristics and SIV seropositivity status was assessed using binary logistic regression. The true prevalence of SIV seropositivity was 26% (95% CI = 20–33). The presence of animals apart from pigs on farm (odds ratio, OR = 2.51, 95% CI = 1.0–6.0), keeping breeding sows for <2 years (OR = 5.9, 95% Cl = 1.8–20), being <1 km from a poultry farm (OR = 2.4, 95% Cl = 1.0–5.7), and purchasing pigs only through pig collectors (OR = 11, 95% CI = 4.3–29) increased the risk of a herd being seropositive to SIV. Our results show that biosecurity to limit the introduction of SIV should be enhanced on farms located in areas of high pig and poultry farm density. While the role that pig collectors play in the transmission of SIV warrants further investigation, swine producers in West Java and Banten should be made aware of the enhanced risk of SIV associated with purchasing of replacements from collectors.



中文翻译:

印度尼西亚西爪哇省和万丹省猪流感(H1N1)血清阳性的牧群级危险因素(2016–2017)

猪可作为禽流感和人类流感病毒的“混合容器”,因此应认为猪流感在大流行性流感病毒株的出现中发挥了中间作用。这项研究的目的是确定印度尼西亚西爪哇省和万丹省农场一级猪流感病毒(SIV)血清阳性的危险因素。从175个养猪场总共采集了649份血液样本,在采样时,向参与者畜群管理者发放了有关常规畜群管理的问卷。使用IDEXX ELISA-test(美国缅因州)测试了每只猪的猪流感病毒血清学状况。使用Rogan和Gladen方法,将SIV血清阳性的明显畜群水平患病率表示为真实的畜群水平患病率,使用马尔可夫链蒙特卡洛贝叶斯方法进行了修改,以解决低流行和高流行人群的问题。牛群水平特征与SIV血清阳性状态之间的关联使用二元逻辑回归分析进行评估。SIV血清阳性的真实患病率为26%(95%CI = 20-33)。农场中除猪外还有动物存在(赔率,OR = 2.51,95%CI = 1.0–6.0),使繁殖母猪保持<2年(OR = 5.9,95%Cl = 1.8–20),<1距离家禽养殖场2公里(OR = 2.4,95%Cl = 1.0–5.7),仅通过收集猪场购买猪(OR = 11,95%CI = 4.3–29)会增加牛群感染SIV的风险。我们的结果表明,应该限制生猪和家禽养殖密度较高地区的农场的生物安全性,以限制SIV的引入。

更新日期:2020-11-12
down
wechat
bug