In plants, hypoxia (low-oxygen stress) is induced by soil waterlogging or submergence and this major abiotic stress has detrimental effects on plant growth, development, distribution, and productivity. To survive low-oxygen stress, plants have evolved a set of morphological, physiological, and biochemical adaptations. These adaptations integrate metabolic acclimation and signaling networks allowing plants to endure or escape from low-oxygen environments by altering their metabolism and growth. Lipids are ubiquitously involved in regulating plant responses to hypoxia and post-hypoxic reoxygenation. In particular, the polyunsaturation of long-chain acyl-CoAs regulates hypoxia sensing in plants by modulating acyl-CoA-binding protein–Group VII ethylene response factor dynamics. Moreover, unsaturated very-long-chain ceramide species protect plants from hypoxia-induced cellular damage by regulating the kinase activity of CONSTITUTIVE TRIPLE RESPONSE1 in the ethylene signaling pathway. Finally, the oxylipin jasmonate specifically regulates plant responses to reoxygenation stress by transcriptionally modulating antioxidant biosynthesis. Here we provide an overview of the roles of lipid remodeling and signaling in plant responses to hypoxia/reoxygenation and their effects on the downstream events affecting plant survival. In addition, we highlight the key remaining challenges in this important field.

在植物中，缺氧（低氧胁迫）是由土壤涝渍或淹没引起的，这种主要的非生物胁迫对植物的生长、发育、分布和生产力具有不利影响。为了在低氧胁迫下生存，植物已经进化出一系列形态、生理和生化适应能力。这些适应整合了代谢适应和信号网络，使植物能够通过改变它们的新陈代谢和生长来忍受或逃离低氧环境。脂质普遍参与调节植物对缺氧和缺氧后复氧的反应。特别是，长链酰基辅酶A的多不饱和通过调节酰基辅酶A结合蛋白-VII组乙烯反应因子动力学来调节植物中的缺氧感应。而且，不饱和的超长链神经酰胺物种通过调节乙烯信号通路中组成三反应1的激酶活性来保护植物免受缺氧诱导的细胞损伤。最后，oxylipin jasmonate 通过转录调节抗氧化剂的生物合成来特异性调节植物对复氧胁迫的反应。在这里，我们概述了脂质重塑和信号传导在植物对缺氧/复氧反应中的作用及其对影响植物存活的下游事件的影响。此外，我们强调了这一重要领域的主要剩余挑战。oxylipin jasmonate 通过转录调节抗氧化生物合成来特异性调节植物对复氧胁迫的反应。在这里，我们概述了脂质重塑和信号传导在植物对缺氧/复氧反应中的作用及其对影响植物存活的下游事件的影响。此外，我们强调了这一重要领域的主要剩余挑战。oxylipin jasmonate 通过转录调节抗氧化生物合成来特异性调节植物对复氧胁迫的反应。在这里，我们概述了脂质重塑和信号传导在植物对缺氧/复氧反应中的作用及其对影响植物存活的下游事件的影响。此外，我们强调了这一重要领域的主要剩余挑战。