Abstract In photodynamic therapy, a beam of incident light on the target causes interactions with the photosensitizing agent in the patient, subsequently killing cancerous cells through chemical and biological processes. The objective of this work was to describe for the first time the use of the FXL-mblue detector in dosimetric applications with irradiations from red LED light and using the UV-Vis spectrophotometry as an evaluation technique. The FXL-mblue samples were irradiated with doses of 2.40 kJ/cm2 up to 21.6 kJ/cm2 using a red LED light system. The results showed good results on uncertainties, sensitivity, reproducibility, repeatability, minimum detectable dose (MDD) and fading times for a promising dosimeter in measurements with visible light. In conclusion, the results indicate good dosimetric characteristics which could be used in quality control of photodynamic therapy measurements.

中文翻译：

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新型 Fricke 二甲苯酚液体检测器掺杂亚甲蓝 (FXL-mblue)，用红色 LED 光照射

摘要 在光动力疗法中，目标上的一束入射光与患者体内的光敏剂相互作用，随后通过化学和生物过程杀死癌细胞。这项工作的目的是首次描述 FXL-mblue 探测器在剂量测定应用中的使用，使用红色 LED 光照射，并使用紫外-可见分光光度法作为评估技术。使用红色 LED 灯系统以 2.40 kJ/cm2 至 21.6 kJ/cm2 的剂量照射 FXL-mblue 样品。结果表明，对于在可见光测量中具有前景的剂量计，其在不确定性、灵敏度、再现性、可重复性、最小可检测剂量 (MDD) 和衰落时间方面取得了良好的结果。综上所述，