A copper-catalyzed reaction protocol for the dehydrogenation of ethylbenzenes into styrene derivatives has been developed. This reaction procedure proceeded well under mild reaction conditions, providing a practical and efficient strategy for the rapid assembly of biologically and pharmaceutically significant molecules, such as vinyl sulfone. Simple alkyl arenes were functionalized via consecutive β-elimination in the presence of N-sulfonylbenzo[d]imidazole with broad substrate scope and good functional group tolerance.

中文翻译：

---

铜催化烷基芳烃的脱氢烯烃磺化

已经开发出铜催化的用于将乙苯脱氢成苯乙烯衍生物的反应方案。该反应过程在温和的反应条件下进行得很好，为生物学和药学上重要的分子（如乙烯基砜）的快速组装提供了实用而有效的策略。在存在N-磺酰基苯并[ d ]咪唑的情况下，通过连续的β-消除作用将简单的烷基芳烃官能化，具有广泛的底物范围和良好的官能团耐受性。