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2,3-Dichloro-5,6-dicyano-1,4-benzoquinone (DDQ)-Mediated Tandem Oxidative-Coupling/Annulation of o-Hydroxyaryl Enaminones with Cycloheptatriene
Synthesis ( IF 2.6 ) Pub Date : 2020-11-11 , DOI: 10.1055/s-0040-1705973
Dongping Cheng 1 , Xiaoliang Xu 2 , Yueqi Pu 1 , Mingliang Wang 1 , Yinqiang Shen 1 , Jing Shen 1 , Jizhong Yan 1
Affiliation  

A DDQ-mediated tandem reaction of easily available o-hydroxy­aryl enaminones and cycloheptatriene is disclosed. It provides an effective and convenient method for the synthesis of 3-(cycloheptatrienyl)-substituted chromones in moderate to excellent yields with good functional group tolerance; this reaction involves an oxidative coupling and intramolecular annulation pathway.



中文翻译:

2,3-二氯-5,6-二氰基-1,4-苯醌(DDQ)介导邻羟基芳基烯胺酮与环庚三烯的串联氧化偶联/环化

公开了容易获得的-羟基芳基烯胺酮和环庚三烯的DDQ介导的串联反应。它提供了一种有效,方便的方法,以中等至优异的产率合成了3-(环庚三烯基)取代的色酮,并具有良好的官能团耐受性。该反应涉及氧化偶联和分子内环化途径。

更新日期:2020-11-12
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