Anhedonic symptoms of posttraumatic stress disorder (PTSD) reflect deficits in reward processing that have significant functional consequences. Although recent evidence suggests that disrupted integrity of fronto‐limbic circuitry is related to PTSD development, including anhedonic PTSD symptoms (posttrauma anhedonia [PTA]), little is known about potential structural biomarkers of long‐term PTA as well as structural changes in fronto‐limbic pathways associated with recovery from PTA over time.

中文翻译：

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创伤后快感缺失风险和恢复的多模态结构神经影像标记：一项前瞻性研究

创伤后应激障碍（PTSD）的快感缺乏症状反映了奖励处理的缺陷，这会产生严重的功能后果。尽管最近的证据表明额叶边缘回路的完整性破坏与 PTSD 的发展有关，包括快感缺乏 PTSD 症状（创伤后快感缺乏 [PTA]），但对于长期PTA 的潜在结构生物标志物以及额叶边缘的结构变化知之甚少。随着时间的推移，与 PTA 恢复相关的边缘通路。