Abstract

Although suicide risk is relevant in First Episode Schizophrenia (FES), little data are reported on suicidal ideation and its longitudinal stability. Aim of this study was: (1) to evaluate incidence rates of suicide attempts, completed suicide and suicidal thinking in FES patients at baseline and along a 24-month follow-up period, (2) to investigate any relevant association of baseline suicidal ideation with psychopathology, and (3) to longitudinally monitor suicidal thinking during the 2-years of follow-up. Participants (n = 149; age = 12–35 years) were assessed with the Brief Psychiatric Rating Scale (BPRS) and the Positive and Negative Syndrome Scale. FES participants showed a 40.8% percentage of baseline suicidal ideation (i.e., BPRS item 4 cutoff score of ≥3) and a 2-year cumulative incidence rate of attempted suicide of 6.1%. One completed suicide (0.7%) was also found during the follow-up. Baseline suicidal ideation was positively correlated with depression and negatively correlated with younger age. These results support a routine monitoring of suicide risk in this young population at the point of entry into early intervention services.

摘要

尽管自杀风险与首发精神分裂症 (FES) 相关，但很少有关于自杀意念及其纵向稳定性的数据报道。本研究的目的是：（1）评估 FES 患者在基线和 24 个月随访期间的自杀企图、完成自杀和自杀念头的发生率，（2）调查基线自杀意念的任何相关关联与精神病理学，以及（3）在 2 年的随访期间纵向监测自杀想法。参与者（n = 149; 年龄 = 12-35 岁）用简要精神病评定量表 (BPRS) 和阳性和阴性综合征量表进行评估。FES 参与者的基线自杀意念百分比为 40.8%（即 BPRS 第 4 项截止分数≥3），2 年累积自杀未遂发生率为 6.1%。随访期间还发现一名完成自杀（0.7%）。基线自杀意念与抑郁呈正相关，与年轻时呈负相关。这些结果支持在进入早期干预服务时对这一年轻人群的自杀风险进行常规监测。