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Microstructure and biological activity of silicon‐doped composite coatings fabricated by micro‐arc oxidation on magnesium alloy
Surface and Interface Analysis ( IF 1.7 ) Pub Date : 2020-11-07 , DOI: 10.1002/sia.6913
Yang Jiao 1 , Xiao‐hui Ni 2 , Guo‐you Zou 2 , Liu‐bao Ren 2 , Lei Yi 3 , Quan‐ming Zhao 2
Affiliation  

Among biomaterials, the mechanical properties of magnesium and its alloys are closest to those of human bone tissue, making these ideal materials for bone tissue repair and replacement. In order to further improve the biocompatibility and biological activity of the magnesium alloy AZ91D, micro‐arc oxidation with a constant‐current power supply mode was employed in this study in a silicate electrolyte solution. The resultant coating surface had a porous structure, and silicon was evenly distributed in it. Further, the results of in vitro experimental studies showed that the silicon‐doped magnesium coating on the surface of the magnesium alloys has no obvious cytotoxicity, and it can induce the proliferation of osteoblasts and promote actin stretching. In addition, it has good biological activity and biocompatibility. Thus, the novel method developed in this study improves the potential for clinical applications of magnesium alloys.

中文翻译:

镁合金微弧氧化制备硅掺杂复合涂层的组织和生物活性

在生物材料中,镁及其合金的机械性能最接近人体骨组织的机械性能,这使它们成为修复和替代骨组织的理想材料。为了进一步改善镁合金AZ91D的生物相容性和生物活性,本研究在硅酸盐电解质溶液中采用了具有恒定电流供电模式的微弧氧化。所得的涂层表面具有多孔结构,并且硅均匀地分布在其中。此外,体外实验研究的结果表明,镁合金表面的硅掺杂镁涂层没有明显的细胞毒性,并且可以诱导成骨细胞的增殖并促进肌动蛋白的拉伸。另外,它具有良好的生物活性和生物相容性。从而,
更新日期:2021-01-14
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