We report the first case of biodegradable airway stent insertion for a patient with bronchomalacia and cystic fibrosis (CF). This female infant with antenatally diagnosed cystic fibrosis developed respiratory distress by three weeks of age. On lower airway examination she was found to have severe left main stem bronchomalacia causing left upper lobe hyperinflation and subsequent right upper lobe collapse. By eight weeks of age she developed life-threatening respiratory failure requiring high pressure invasive ventilation. A biodegradable bronchial stent was inserted to the left main bronchus at thirteen weeks of age with successful extubation from invasive respiratory support four days later. A second biodegradable stent was inserted nine weeks later, due to persistent bronchomalacia following stent degradation and redevelopment of oxygen requirement. She was discharged home off all respiratory support eight weeks later and has remained well, requiring no further surgical intervention for bronchomalacia to date, now age three years.

中文翻译：

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在患有严重支气管软化症和囊性纤维化的婴儿中成功插入可生物降解支架

我们报告了首例用于支气管软化症和囊性纤维化 (CF) 患者的可生物降解气道支架置入术。这名产前诊断为囊性纤维化的女婴在三周大时出现呼吸窘迫。下气道检查发现她有严重的左主干支气管软化，导致左上叶过度充气，随后右上叶塌陷。到八周大时，她出现了危及生命的呼吸衰竭，需要进行高压有创通气。在 13 周龄时将可生物降解的支气管支架插入左主支气管，4 天后从侵入性呼吸支持中成功拔管。九周后插入第二个可生物降解支架，由于支架降解和氧气需求重建后的持续性支气管软化。八周后，她停止了所有呼吸支持，出院回家，并且一直保持良好状态，迄今为止，支气管软化症不需要进一步的手术干预，现在她已经三岁了。