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Unraveling the Enigmatic Origin of Neuroblastoma
Cancer Cell ( IF 50.3 ) Pub Date : 2020-11-09 , DOI: 10.1016/j.ccell.2020.10.016
Zhihui Liu , Carol J. Thiele

The cell of origin of neuroblastoma is mysterious due to the complexity of neural crest derivatives. In this issue of Cancer Cell, Dong et al. compare the transcriptomes of human embryos, fetal adrenal glands, and neuroblastoma at single-cell level and find a chromaffin cell identity of neuroblastoma.



中文翻译:

揭示神经母细胞瘤的神秘起源

由于神经rest衍生物的复杂性,神经母细胞瘤的起源细胞是神秘的。在本期的癌细胞中,Dong等。在单细胞水平上比较人类胚胎,胎儿肾上腺和神经母细胞瘤的转录组,并找到神经母细胞瘤的嗜铬细胞身份。

更新日期:2020-11-09
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