Abstract Ralstonia solanacearum is the causal agent of Moko disease in bananas, which in the state of Sergipe in northeastern Brazil causes “Sergipe facies”. This disease induces atypical symptoms similar to those of Bugtok disease in the Philippines. This study was conducted to sequence, assemble, and annotate the genomes of the Sergipe facies-causing isolates SFC and IBSBF2570 (sequevar IIA-53) and compare their genomes with two representative isolates causing Bugtok disease. The genomes were sequenced and assembled, resulting in lengths of 5.58 Mb (SFC) and 5.46 Mb (IBSBF2570) in 185 and 174 contigs, respectively. The isolates of Sergipe facies and Bugtok disease showed similarities in their gene contents. We identified 5,668 information clusters, 3,752 of which were shared by all genomes (core genes). Moreover, 3,585 single-copy genes were identified. Isolates causing Bugtok disease exclusively shared 266 more information clusters than the isolates causing Sergipe facies. These results suggest that Sergipe facies and Bugtok disease isolates show high genomic similarity. However, the similarity is even greater between the Bugtok disease isolates. This may be because of their longer period of interaction compared to Sergipe facies isolates.

中文翻译：

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两株青枯病菌的基因组测序及与布托克病株的比较分析

摘要 Ralstonia solanacearum 是香蕉莫科病的病原体，在巴西东北部塞尔吉比州引起“塞尔吉比相”。这种疾病会引起与菲律宾布格托克病相似的非典型症状。本研究旨在对引起 Sergipe 相的分离株 SFC 和 IBSBF2570（sequevar IIA-53）的基因组进行测序、组装和注释，并将它们的基因组与引起 Bugtok 病的两个代表性分离株进行比较。对基因组进行测序和组装，分别在 185 个和 174 个重叠群中产生了 5.58 Mb (SFC) 和 5.46 Mb (IBSBBF2570) 的长度。Sergipe 相和 Bugtok 病的分离株在基因含量上表现出相似性。我们确定了 5,668 个信息簇，其中 3,752 个由所有基因组（核心基因）共享。此外，3，鉴定了 585 个单拷贝基因。引起 Bugtok 病的分离株比引起 Sergipe 相的分离株共享了 266 个以上的信息簇。这些结果表明 Sergipe 相和 Bugtok 病分离株显示出高度的基因组相似性。然而，Bugtok 病株之间的相似性甚至更大。这可能是因为与 Sergipe 相分离株相比，它们的相互作用时间更长。